We are combatting the stigma behind the opioid epidemic.

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Creating an equitable and sustainable medical system that provides Naloxone and saves lives.

Our Mission

To directly provide Naloxone to all patients at-risk of overdose, and to have that effort led by healthcare providers and medical spaces.

Six pillars of service

  • TNP is at the forefront of building naloxone distribution programs that are accessible, scalable, and sustainable across diverse community practice environments. Naloxone is distributed through TNP-led programs, community donations, innovative vending machine initiatives, and direct distribution at community events ensuring multiple, low-barrier pathways to access. Through strategic partnerships and a commitment to equity, TNP reaches people where they are, strengthening overdose prevention efforts and saving lives.

  • TNP prides on being a trusted national source of data and analysis on naloxone access and overdose risk. Our expanded data and research capacity reinforced the evidence that community-based naloxone distribution saves lives, reduces healthcare burden, and advances equity.

  • TNP is a leading resource for scientifically grounded, stigma free naloxone distribution and overdose response solutions. We develop tailored education and training materials for both laypeople and clinicians, informed by community and provider focus groups to ensure relevance, accessibility, and real world effectiveness. Hosting comprehensive, program specific toolkits online, supporting partners in implementing best practices across both medical and community spaces.

  • TNP recognizes the deep inequities faced by populations at higher risk for overdose and is committed to taking meaningful, sustained action to address and close those gaps. We put this commitment into practice by expanding access to naloxone and harm reduction tools, building strong partnerships with community based organizations, and prioritizing outreach in rural, marginalized, and underserved communities.

  • TNP stewards resources with care to ensure long-term impact. Through transparent financial practices and strategic growth, we strengthen our ability to expand access to naloxone and respond to evolving community needs.

  • TNP works to remove barriers and advance policies that make naloxone easier to access and use. By collaborating with policymakers, healthcare systems, and advocates, we help shape a regulatory landscape that prioritizes public health and saves lives.

Born in Colorado, 2021

A smiling nurse in blue scrubs sits with a patient wearing glasses and a gray hoodie, in a hospital setting.

The first chapter of The Naloxone Project involved quickly recruiting hospitals and emergency departments throughout the state. As of 2023, there are 107 participating hospital facilities in Colorado. These represent 1.9 million emergency department visits in 2022, which is 97% of all emergency department visits for Colorado.

Over 2,500 donated naloxone kits were dispensed from participating hospitals during this timeframe. 30 of the participating sites are rural or critical access facilities, emphasizing the focus on equitable access to naloxone for even the most
remote communities.

Colorado also established a "leave-behind" program with emergency medical services and the police department in the rural northwest part of the state. Multiple examples of model legislation were passed during this timeframe to further assist in the ease and reimbursement of take-home naloxone distribution from hospitals.

In addition, the Colorado chapter has 22 government, nonprofit, and other partners that support its work.

WHAT WE’VE ACCOMPLISHED

How we got here

In 2022, The Naloxone Project deepened its commitment to creating a future where there is “no wrong way” to receive naloxone—from hospitals to community clinics to first responders. Our work strategically spans healthcare settings, public policy, and prehospital systems, ensuring access wherever the need arises.

That year, we introduced our first state chapter in Colorado and launched the MOMs (Maternal Overdose Matters) Initiative, which focuses on delivering overdose education and naloxone to pregnant and parenting patients directly within hospital maternity and perinatal units.

In parallel, we established CPACC—the Colorado Prehospital Addiction Care Consortium as part of our efforts to build an evidence-based, compassionate prehospital care system for individuals with substance use disorders. This initiative equips EMS and law enforcement agencies across Colorado with naloxone “leave-behind” programs and harm reduction strategies, improving equity in access and linking overdose survivors to community-based care.

By early 2023, we had expanded nationally, forming chapters in 10 additional states. Our Board of Directors convened its inaugural annual meeting in January 2023 and assigned members to support each new chapter, ensuring they benefit from Colorado’s model while tailoring strategies locally.

Looking ahead, The Naloxone Project continues to broaden its reach into new hospital departments, clinics, and prehospital settings. Legislative advocacy remains a core, pillar targeting both regulatory support and reimbursement mechanisms to make naloxone distribution sustainable in healthcare and community systems.

WHAT WE’VE ACCOMPLISHED

The American Medical Association and The Naloxone Project are working together to remove barriers to naloxone access. Naloxone is a proven tool to reverse opioid overdoses, yet too many people still struggle to access it when it’s needed most. By encouraging physicians to prescribe it, making it available in schools, workplaces, and public spaces, and ensuring affordability, we can prevent countless unnecessary deaths.

This initiative calls on health professionals, policymakers, employers, and communities to join in expanding naloxone distribution—because timely access means the difference between life and death.

Expanding Access to Naloxone Saves Lives

Still curious about our work and key findings?

Reach out to us with any questions you have— we’re happy to help you.

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No stigma

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Equitable

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Sustainable

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Accessible

✔︎ No stigma ✔︎ Equitable ✔︎ Sustainable ✔︎ Accessible