We are combatting the stigma behind the opioid epidemic.
Creating an equitable and sustainable medical system that provides Naloxone and saves lives.
Our Mission
The Naloxone Project is combating the stigma behind the opioid epidemic by creating an equitable and sustainable medical system that provides naloxone and saves lives.
Six pillars of service
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TNP is at the forefront of building naloxone distribution programs that are accessible, scalable, and sustainable across diverse community practice environments. Naloxone is distributed through TNP-led programs, community donations, innovative vending machine initiatives, and direct distribution at community events ensuring multiple, low-barrier pathways to access. Through strategic partnerships and a commitment to equity, TNP reaches people where they are, strengthening overdose prevention efforts and saving lives.
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TNP prides on being a trusted national source of data and analysis on naloxone access and overdose risk. Our expanded data and research capacity reinforced the evidence that community-based naloxone distribution saves lives, reduces healthcare burden, and advances equity.
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TNP is a leading resource for scientifically grounded, stigma free naloxone distribution and overdose response solutions. We develop tailored education and training materials for both laypeople and clinicians, informed by community and provider focus groups to ensure relevance, accessibility, and real world effectiveness. Hosting comprehensive, program specific toolkits online, supporting partners in implementing best practices across both medical and community spaces.
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TNP recognizes the deep inequities faced by populations at higher risk for overdose and is committed to taking meaningful, sustained action to address and close those gaps. We put this commitment into practice by expanding access to naloxone and harm reduction tools, building strong partnerships with community based organizations, and prioritizing outreach in rural, marginalized, and underserved communities.
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TNP stewards resources with care to ensure long-term impact. Through transparent financial practices and strategic growth, we strengthen our ability to expand access to naloxone and respond to evolving community needs.
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TNP works to remove barriers and advance policies that make naloxone easier to access and use. By collaborating with policymakers, healthcare systems, and advocates, we help shape a regulatory landscape that prioritizes public health and saves lives.
Born in Colorado, 2021
The Naloxone Project is working to ensure that naloxone is available wherever it is needed, across hospitals, communities, and first response systems nationwide.
Since our founding, we have distributed more than 121,000 doses of naloxone, including 59,000 in 2025 alone, reaching individuals, families, and communities at critical moments. In the past year, we expanded to 15 state chapters, building a coordinated national network that moves naloxone quickly, equitably, and at scale.
The Naloxone Project continues to expand access across new states, new care settings, and new communities—ensuring that naloxone is not only available, but expected.
We are building toward a future where overdose prevention is fully integrated into healthcare, where first responders are equipped to both save lives and connect people to care, and where communities have the tools and knowledge to act before tragedy occurs.
Because saving a life should never depend on where you are, who you are, or how you access care.
WHAT WE’VE ACCOMPLISHED
How we got here
Our approach is rooted in a simple belief: there should be no wrong way to access naloxone.
In 2025, we advanced this vision through a coordinated strategy that spans healthcare, community systems, and public policy. We strengthened hospital-based distribution, expanded outpatient and perinatal care programs, and scaled prehospital initiatives that equip first responders with both naloxone and pathways to treatment.
At the same time, we invested in the systems that sustain long-term impact. We trained thousands of healthcare professionals and community members, expanded our data and research capabilities, and supported policies that remove barriers to naloxone access.
This work is guided by evidence and shaped by the communities we serve. In 2025, we deepened our commitment to equity by prioritizing rural and underserved populations, launching community advisory efforts, and ensuring that those most affected by overdose are helping to lead the solutions.
As our national network grows, so does our ability to respond—pairing local leadership with shared infrastructure to deliver naloxone where it is needed most.
WHAT WE’VE ACCOMPLISHED
Expanding Access to Naloxone Saves Lives
The American Medical Association and The Naloxone Project are working together to remove barriers to naloxone access. Naloxone is a proven tool to reverse opioid overdoses, yet too many people still struggle to access it when it’s needed most. By encouraging physicians to prescribe it, making it available in schools, workplaces, and public spaces, and ensuring affordability, we can prevent countless unnecessary deaths.
This initiative calls on health professionals, policymakers, employers, and communities to join in expanding naloxone distribution—because timely access means the difference between life and death.
Still curious about our work and key findings?
Reach out to us with any questions you have— we’re happy to help you.